Coronary Artery Disease
Screening Tests
What is coronary artery disease?
Coronary artery disease (CAD) is arteriosclerosis of the inner lining
of the blood vessels that supply blood to the heart. CAD is a common
form of heart disease and is a major cause of illness and death.
CAD begins when hard cholesterol substances (plaques) are deposited
within a coronary artery. (The coronary arteries arise from the
aorta, which is adjacent to the heart.) The plaques can cause a tiny
clot to form which can obstruct the flow of blood to the heart
muscle. Symptoms of CAD include 1) chest pain (angina pectoris) from
inadequate blood flow to the heart; 2) heart attack (acute myocardial
infarction), from the sudden total blockage of a coronary artery; or
3) sudden death, due to a fatal rhythm disturbance.
What is the purpose of screening tests for CAD?
In many
patients, the first symptom of CAD is myocardial infarction or sudden death,
with no preceding chest pain as a warning. For this reason, doctors perform
screening tests to detect signs of CAD before serious medical events occur.
Screening tests are of particular importance for patients with risk factors for
CAD. These risk factors include a family history of CAD at relatively young
ages, an abnormal serum cholesterol profile, cigarette smoking, elevated blood
pressure (hypertension), and diabetes mellitus.
What are common initial screening tests for CAD?
Initial screening for CAD commonly involves stressing the heart under
controlled conditions. These stress tests are able to detect the
presence of flow-limiting blockages in the coronary arteries,
generally in the range of at least a 50% reduction in the diameter of
at least one of the three major coronary arteries. There are two
basic types of stress tests; those that involve exercising the
patient to stress the heart (exercise cardiac stress tests), and
those that involve chemically stimulating the heart directly to mimic
the stress of exercise (physiologic stress testing). Physiologic
stress testing can be used for patients who are unable to exercise.
Next: Exercise Cardiac Stress Test (Treadmill Stress Test) »
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From the Doctors at MedicineNet.com  |
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- Cholesterol - Learn about cholesterol and how to lower LDL cholesterol. Read in-depth cholesterol information on a low cholesterol diet, normal ratio (levels), treatment for high cholesterol and more. Source:MedicineNet
- Angina - Learn about the causes and symptoms of angina like pressure, heaviness, tightening, squeezing, and aching across the chest. There are two types of angina, stable (the most common) and unstable. Source:MedicineNet
- Heart Attack - Overview on heart attack (myocardial infarction) and heart attack symptoms including signs of a heart attack, includes causes, risk factors, prevention, and treatment. Produced by medical doctors. Source:MedicineNet
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