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 Heart Disease Main Article |  Glossary |  Heart Disease Index 

Heart Disease Glossary of Terms

The following are health and medical definitions of terms that appear in the Heart Disease article.

Abdominal: Relating to the abdomen, the belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
See the entire definition of Abdominal

Abdominal pain: Pain in the belly (the abdomen). Abdominal pain can come from conditions affecting a variety of organs. The abdomen is an anatomical area that is bounded by the lower margin of the ribs above, the pelvic bone (pubic ramus) below, and the flanks on each side. Although abdominal pain can arise from the tissues of the abdominal wall that surround the abdominal cavity (the skin and abdominal wall muscles), the term abdominal pain generally is used to describe pain originating from organs within the abdominal cavity (from beneath the skin and muscles). These organs include the stomach, small intestine, colon, liver, gallbladder, and pancreas.
See the entire definition of Abdominal pain

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
See the entire definition of Abnormal

Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
See the entire definition of Acute

Adjacent: Lying nearby. Related terms include superjacent, subjacent, and circumjacent. From ad-, near + the Latin jacere, to lie = to lie near.

Adrenaline: A substance produced by the medulla (inside) of the adrenal gland, adrenaline (the official name in the British Pharmacopoeia) is synonymous with epinephrine. Technically speaking, adrenaline is a sympathomimetic catecholamine. It causes quickening of the heart beat, strengthens the force of the heart's contraction, opens up the bronchioles in the lungs and has numerous other effects. The secretion of adrenaline by the adrenal is part of the "fight-or-flight" reaction that we have in response to being frightened.

Alcohol: An organic chemical in which one or more hydroxyl (OH) groups are attached to carbon (C) atoms in place of hydrogen (H) atoms. Common alcohols include ethyl alcohol or ethanol (found in alcoholic beverages), methyl alcohol or methanol (can cause blindness) and propyl alcohol or propanol (used as a solvent and antiseptic ). Rubbing alcohol is a mixture of acetone , methyl isobutyl ketone, and ethyl alcohol. In everyday talk, alcohol usually refers to ethanol as, for example, in wine, beer, and liquor. It can cause changes in behavior and be addictive.
See the entire definition of Alcohol

Anatomy: The study of form. Gross anatomy involves structures that can be seen with the naked eye. It is as opposed to microscopic anatomy (or histology) which involves structures seen under the microscope. Traditionally, both gross and microscopic anatomy have been studied in the first year of medical school in the U.S. The most celebrated textbook of anatomy in the English-speaking world is Gray's Anatomy, still a useful reference book. The word "anatomy" comes from the Greek ana- meaning up or through + tome meaning a cutting. Anatomy was once a "cutting up" because the structure of the body was originally learned through dissecting it, cutting it up. The abbreviation for anatomy is anat.

Angina: Chest pain due to an inadequate supply of oxygen to the heart muscle. The chest pain of angina is typically severe and crushing. There is a feeling just behind the breastbone (the sternum) of pressure and suffocation.
See the entire definition of Angina

Angiogram: An x-ray of blood vessels which can be seen because the patient receives an injection of dye to outline the vessels on the x-ray.

Angiography: A procedure performed to view blood vessels after injecting them with a radioopaque dye that outlines them on x-ray. This technique can be usefully used to look at arteries in many areas of the body, including the brain, neck (carotids), heart, aorta, chest, pulmonary circuit, kidneys, gastrointestinal tract, and limbs.

Angioplasty: Procedure with a balloon-tipped catheter to enlarge a narrowing in a coronary artery. Also called Percutaneous Transluminal Coronary Angioplasty (PTCA).

Aorta: The largest artery in the body, the aorta arises from the left ventricle of the heart, goes up (ascends) a little ways, bends over (arches), then goes down (descends) through the chest and through the abdomen to where ends by dividing into two arteries called the common iliac arteries that go to the legs.
See the entire definition of Aorta

Arm: 1. In popular usage, the appendage that extends from the shoulder to the hand. However, the medical definition refers to the upper extremity extending from the shoulder only to the elbow, excluding the forearm, which extends from the elbow to the wrist. The arm contains one bone: the humerus. 2. In a randomized clinical trial, any of the treatment groups. Most randomized trials have two "arms," but some have three "arms," or even more.

Artery: A vessel that carries blood high in oxygen content away from the heart to the farthest reaches of the body. Since blood in arteries is usually full of oxygen, the hemoglobin in the red blood cells is oxygenated. The resultant form of hemoglobin (oxyhemoglobin) is what makes arterial blood look bright red.
See the entire definition of Artery back to top

Aspirin: A good example of a tradename that entered into the language, Aspirin was once the Bayer trademark for acetylsalicylic acid .
See the entire definition of Aspirin

Asymptomatic: Without symptoms. For example, an asymptomatic infection is an infection with no symptoms.

Atenolol : A medication that blocks the action of a portion of the involuntary nervous system that stimulates the pace of the heartbeat. By blocking the action of these nerves, atenolol reduces the heart rate and is useful in treating abnormally rapid heart rhythms. Atenolol also reduces the force of heart muscle contraction, lowers blood pressure, and is helpful in treating angina . It is also used for the prevention of migraine headaches and the treatment of certain types of tremors. The brand name is Tenormin. Generic is available.
See the entire definition of Atenolol

Atypical: Not typical, not usual, not normal, abnormal. Atypical is often used to refer to the appearance of precancerous or cancerous cells.

Baseline: 1. Information gathered at the beginning of a study from which variations found in the study are measured.
2. A known value or quantity with which an unknown is compared when measured or assessed.
3. The initial time point in a clinical trial, just before a participant starts to receive the experimental treatment which is being tested. At this reference point, measurable values such as CD4 count are recorded. Safety and efficacy of a drug are often determined by monitoring changes from the baseline values.

Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.

Blood clot: Blood that has been converted from a liquid to a solid state. Also called a thrombus .
See the entire definition of Blood clot

Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".

Bone: Bone is the substance that forms the skeleton of the body. It is composed chiefly of calcium phosphate and calcium carbonate . It also serves as a storage area for calcium, playing a large role in calcium balance in the blood.
See the entire definition of Bone

Breast bone: Familiar name for the sternum, the long flat bone in the middle of the front of the chest.
See the entire definition of Breast bone

Bypass: An operation in which a surgeon creates a new tubular pathway for the movement of fluids and/or other substances in the body.
See the entire definition of Bypass

Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily.

Cardiac: Having to do with the heart.
See the entire definition of Cardiac

Cardiologist: A doctor who specializes in treating heart disorders.

Catheter: A thin, flexible tube . For example, a catheter placed in a vein provides a pathway for giving drugs, nutrients, fluids, or blood products. Samples of blood can also be withdrawn through the catheter.
See the entire definition of Catheter back to top

Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum .
See the entire definition of Chest

Chest pain: There are many causes of chest pain. One is angina which results from inadequate oxygen supply to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. Chest pain can also be due to a heart attack (coronary occlusion) and other important diseases such as, for example, dissection of the aorta and a pulmonary embolism. Do not try to ignore chest pain and "work (or play) though it." Chest pain is a warning to seek medical attention.

Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
See the entire definition of Cholesterol

Computerized tomography: Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them in pictures.
See the entire definition of Computerized tomography

Coronary angiography: The most accurate method (the "gold standard") for evaluating and defining coronary artery disease (CAD). Coronary angiography is used to identify the exact location and severity of CAD.
See the entire definition of Coronary angiography

Coronary arteries: The vessels that supply the heart muscle with blood rich in oxygen. They are called the coronary arteries because they encircle the heart in the manner of a crown. The word "coronary" comes from the Latin "corona" and Greek "koron" meaning crown. Like other arteries, the coronaries may be subject to arteriosclerosis (hardening of the arteries). There are a number of coronary arteries. Those most often bypassed today include the right coronary artery, the posterior descending coronary artery, the left main coronary artery, the left anterior descending coronary artery and the left circumflex coronary artery. Plaques obstructing the coronary arteries may also be treated by balloon angioplasty , stents, and other techniques.
See the entire definition of Coronary arteries

Coronary artery disease: A major cause of illness and death, coronary artery disease (CAD) begins when hard cholesterol substances (plaques) are deposited within a coronary artery.
See the entire definition of Coronary artery disease

Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
See the entire definition of Diabetes

Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
See the entire definition of Diagnosis

ECG: Abbreviation for electrocardiogram or EKG. The K is from "kardio" (in German).

Echocardiography: Echocardiography is a diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures. It can measure cardiac output and is a sensitive test for inflammation around the heart (pericarditis). It can also be used to detect abnormal anatomy or infections of the heart valves.

Ejection fraction: The portion of blood that is pumped out of a filled ventricle as a result of a heartbeat.
See the entire definition of Ejection fraction

Electrocardiogram : A recording of the electrical activity of the heart. An electrocardiogram is a simple, non-invasive procedure. Electrodes are placed on the skin of the chest and connected in a specific order to a machine that, when turned on, measures electrical activity all overaround the heart. Output is usually in the form of a long scroll of paper displaying a printed graph of activity. Newer models output the data directly to a computer and screen, although a print-out may still be made.
See the entire definition of Electrocardiogram

Emergency department: The department of a hospital responsible for the provision of medical and surgical care to patients arriving at the hospital in need of immediate care. Emergency department personnel may also respond to certain situations within the hospital such cardiac arrests.
See the entire definition of Emergency department

Family history: The family structure and relationships within the family, including information about diseases in family members.
See the entire definition of Family history back to top

Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
See the entire definition of Fatigue

Genetic: Having to do with genes and genetic information.

Groin: In anatomy, the area where the upper thigh meets the trunk. More precisely, the fold or depression marking the juncture of the lower abdomen and the inner part of the thigh.
See the entire definition of Groin

Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
See the entire definition of Heart

Heart attack: The death of heart muscle due to the loss of blood supply. The loss of blood supply is usually caused by a complete blockage of a coronary artery, one of the arteries that supplies blood to the heart muscle. Death of the heart muscle, in turn, causes chest pain and electrical instability of the heart muscle tissue.
See the entire definition of Heart attack

Heart disease: Any disorder that affects the heart. Sometimes the term "heart disease" is used narrowly and incorrectly as a synonym for coronary artery disease. Heart disease is synonymous with cardiac disease but not with cardiovascular disease which is any disease of the heart or blood vessels. Among the many types of heart disease, see, for example: Angina; Arrhythmia; Congenital heart disease; Coronary artery disease (CAD); Dilated cardiomyopathy; Heart attack (myocardial infarction); Heart failure; Hypertrophic cardiomyopathy; Mitral regurgitation; Mitral valve prolapse; and Pulmonary stenosis.

Heart muscle: A type of muscle with unique features only found in the heart. The heart muscle, or cardiac muscle, is medically called the myocardium ("myo-" being the prefix denoting muscle).

Heart rate: The number of heart beats per unit time, usually per minute. The heart rate is based on the number of contractions of the ventricles (the lower chambers of the heart). The heart rate may be too fast ( tachycardia ) or too slow ( bradycardia ). The pulse is bulge of an artery from the wave of blood coursing through the blood vessel as a result of the heart beat. The pulse is often taken at the wrist to estimate the heart rate.
See the entire definition of Heart rate

High blood pressure : Also known as hypertension, high blood pressure is, by definition, a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
See the entire definition of High blood pressure

Hospital: It may seem unnecessary to define a "hospital" since everyone knows the nature of a hospital. A hospital began as a charitable institution for the needy, aged, infirm, or young.
See the entire definition of Hospital

Hypertension: High blood pressure , defined as a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
See the entire definition of Hypertension

Indicate: In medicine, to make a treatment or procedure advisable because of a particular condition or circumstance. For example, certain medications are indicated for the treatment of hypertension during pregnancy while others are contraindicated.

Infarction: The formation of an infarct, an area of tissue death due to a local lack of oxygen.
See the entire definition of Infarction

Iodine: An essential element in the diet used by the thyroid gland to make thyroid hormones .
See the entire definition of Iodine

Jaw: The bones below the mouth (the mandible) and the bone above the mouth just above the mouth (the maxilla). The word jaw comes from the Anglo-Saxon ceowan meaning to chew.
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Lipid: Another word for "fat." (Please see the various meanings of Fat .) A lipid is more formally defined as a substance such as a fat, oil or wax that dissolves in alcohol but not in water. Lipids contain carbon, hydrogen and oxygen but have far less oxygen proportionally than carbohydrates .
See the entire definition of Lipid

Malaise: A vague feeling of discomfort, one that cannot be pinned down but is often sensed as "just not right."
See the entire definition of Malaise

Medication: 1. A drug or medicine. 2. The administration of a drug or medicine. (Note that "medication" does not have the dangerous double meaning of "drug.")

Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."

Myocardial infarction: A heart attack . Abbreviated MI.
See the entire definition of Myocardial infarction

Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza, medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain, jaundice, fever, or bleeding, a physician should be consulted.

Nutrition : 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.
See the entire definition of Nutrition

Obesity: The state of being well above one's normal weight.
See the entire definition of Obesity

Oxygen: A colorless, odorless and tasteless gas that makes up about 20% of the air we breathe (and at least half the weight of the entire solid crust of the earth) and which combines with most of the other elements to form oxides. Oxygen is essential to human, animal and plant life.
See the entire definition of Oxygen

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
See the entire definition of Pain

Perfusion: A chemotherapy technique that may be used when melanoma occurs on an arm or leg. The flow of blood to and from the limb is stopped for a while with a tourniquet, and anticancer drugs are put directly into the blood of the limb. This allows the patient to receive a high dose of drugs in the area where the melanoma occurred.

Pericardial: Referring to the pericardium, the sac of fibrous tissue that surrounds the heart. The inner surface of the pericardium is lined by a layer of flat cells (mesothelial cells). The pericardial sac normally contains a small amount of fluid which acts as a lubricant to allow normal heart movement within the chest. A pericardial effusion refers to the presence of too much pericardial fluid, a serous fluid of a pale yellow color, within the pericardium.

Pericardial sac: A conical sac of fibrous tissue which surrounds the heart and the roots of the great blood vessels. Also called the pericardium .
See the entire definition of Pericardial sac

Peripheral: Situated away from the center, as opposed to centrally located.
See the entire definition of Peripheral

Peripheral artery disease: A form of peripheral vascular disease in which there is partial or total blockage of an artery, usually one leading to a leg or arm. Leg artery disease and arm artery disease are somewhat different.
See the entire definition of Peripheral artery disease back to top

Plaque: 1. An semi-hardened accumulation of substances from fluids that bathe an area. Examples include dental plaque and cholesterol plaque.
See the entire definition of Plaque

Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation.

Radioactive: Emitting energy waves due to decaying atomic nuclei. Radioactive substances are used in medicine as tracers for diagnosis, and in treatment to kill cancerous cells.
See the entire definition of Radioactive

Rest: 1. Repose. Relaxation.
2. A fragment of embryonic tissue that has been retained after the period of embryonic development. Also called an embryonic rest.

Septum: A word borrowed from the Latin "saeptum" meaning a "dividing wall or enclosure."
See the entire definition of Septum

Shoulder: A structure made up of two main bones: the scapula (shoulder blade) and the humerus (the long bone of the upper arm). The end of the scapula, called the glenoid, is a socket into which the head of the humerus fits, forming a flexible ball-and-socket joint. The scapula is an unusually shaped bone. It extends up and around the shoulder joint at the rear to create a roof called the acromion and around the shoulder joint at the front to constitute the coracoid process. The shoulder joint is cushioned by cartilage that covers the face of the glenoid socket and the head of the humerus. The joint is stabilized by a ring of fibrous cartilage around the glenoid socket that is called the labrum. Ligaments connect the bones of the shoulder and tendons join these bones to surrounding muscles. The biceps tendon attaches the biceps muscle to the shoulder and helps stabilize the joint. Four short muscles that originate on the scapula pass around the shoulder where their tendons fuse together to form the rotator cuff.

Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.


See the entire definition of Skin

Stent: A tube designed to be inserted into a vessel or passageway to keep it open.
See the entire definition of Stent

Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
See the entire definition of Stress

Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
See the entire definition of Surgery

Sweating: The act of secreting fluid from the skin by the sweat (sudoriferous) glands. These are small tubular glands situated within and under the skin (in the subcutaneous tissue). They discharge by tiny openings in the surface of the skin.
See the entire definition of Sweating

Tenormin: See: Atenolol.

Thallium: A metallic element having the symbol Tl and the atomic number 81 and an atomic weight of about 204.
See the entire definition of Thallium

Tissue: A tissue in medicine is not like a piece of tissue paper. It is a broad term that is applied to any group of cells that perform specific functions. A tissue in medicine need not form a layer. Thus,

  • The bone marrow is a tissue;
  • Connective tissue consists of cells that make up fibers in the framework supporting other body tissues; and
  • Lymphoid tissue is the part of the body's immune system that helps protect it from bacteria and other foreign entities.

Tomography: The process for generating a tomogram , a two-dimensional image of a slice or section through a three-dimensional object. Tomography achieves this remarkable result by simply moving an x-ray source in one direction as the x-ray film is moved in the opposite direction during the exposure to sharpen structures in the focal plane, while structures in other planes appear blurred. The tomogram is the picture; the tomograph is the apparatus; and tomography is the process.
See the entire definition of Tomography back to top

Tongue: The tongue is a strong muscle anchored to the floor of the mouth. It is covered by the lingual membrane which has special areas to detect tastes.
See the entire definition of Tongue

Treadmill: A machine with a moving strip on which one walks without moving forward. A treadmill was originally a wide wheel turned by the weight of people climbing on steps around its edge, used in the past to provide power for machines or as a punishment in prisons.
See the entire definition of Treadmill

Treadmill test: A test (sometimes called the exercise treadmill test or exercise test) in which a continuous electrocardiogram ( ECG or EKG) recording of the heart is made as the patient performs increasing levels of exercise on the treadmill which is tilted to produce the effect of going up a small hill. The patient can stop the test at any time, if necessary. Afterwards the patient has heart and blood pressure checked.
See the entire definition of Treadmill test

Vein: A blood vessel that carries blood low in oxygen content from the body back to the heart. The deoxygenated form of hemoglobin (deoxyhemoglobin) in venous blood makes it appear dark. Veins are part of the afferent wing of the circulatory system which returns blood to the heart.
See the entire definition of Vein

Ventricle: A chamber of an organ. For example, the four connected cavities (hollow spaces) in the central portion of the brain and the lower two chambers of the heart are called ventricles.

Vessel: A tube in the body that carries fluids: blood vessels or lymph vessels.

X-ray: 1. High-energy radiation with waves shorter than those of visible light. X-rays possess the properties of penetrating most substances (to varying extents), of acting on a photographic film or plate (permitting radiography), and of causing a fluorescent screen to give off light (permitting fluoroscopy). In low doses X-rays are used for making images that help to diagnose disease, and in high doses to treat cancer . Formerly called a Roentgen ray. 2. An image obtained by means of X-rays.
See the entire definition of X-ray back to top

 Heart Disease Main Article |  Glossary |  Heart Disease Index 




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